Computerized testing of neurocognitive function in euthymic bipolar patients compared to those with mild cognitive impairment and cognitively healthy controls Academic Article uri icon

abstract

  • Impaired neuropsychological functioning in bipolar patients, even when euthymic, is well documented [1, 2] . Meta-analyses [3–5] reveal a consistent pattern of impair- ment, particularly in attention, verbal learning/memory, and executive function. These deficits have been shown to persist over periods of at least 1–5 years [6–9] . Both meta-analyses [3, 10] and a critical review [11] suggest that these deficits may even constitute a neurocognitive endophenotype for bipolar disorder. While effect sizes were small to medium (d ! 0.5), significant differences

publication date

  • January 1, 2011