Possible recurrent pandemic (H1N1) 2009 infection, Israel Academic Article uri icon


  • To the Editor: We report 2 cases of possible recurrent laboratoryconfirmed infection with pandemic (H1N1) 2009 virus in Israel. Patient 1, a 24-year-old man, had Noonan syndrome (1, 2). He was hospitalized on August 10, 2009, because of highgrade fever and cough. At admission, a nasopharyngeal specimen was collected for pandemic (H1N1) 2009 virus real- time reverse transcription–PCR (RT-PCR)(ABI 7500; Applied Biosystems, Foster City, CA, USA) for the pandemic hemagglutinin gene; a validated in-house protocol developed at Israel Central Virology Laboratory was used, as previously described (3). Briefly, the in- house assay was validated against the assay for pandemic (H1N1) 2009 virus developed by the Centers for Disease Control and Prevention (CDC; Atlanta, GA, USA). The in-house assay was as sensitive as the CDC assay; however, the in-house primers and probes …

publication date

  • January 1, 2010