selected publications
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academic article
- H-Ras nanocluster stability regulates the magnitude of MAPK signal output. PLOS ONE. 5:e11991. 2010
- K-ras nanoclustering is subverted by overexpression of the scaffold protein galectin-3. Cancer research. 68:6608-6616. 2008
- Galectin-1 is a novel structural component and a major regulator of h-ras nanoclusters. Molecular biology of the cell. 19:1404-1414. 2008
- The Ras inhibitor farnesylthiosalicylic acid (Salirasib) disrupts the spatiotemporal localization of active Ras: a potential treatment for cancer. Methods in enzymology. 439:467-489. 2008
- Intercellular transfer of oncogenic H-Ras at the immunological synapse. PLOS ONE. 2:e1204. 2007
- FRAP beam-size analysis to measure palmitoylation-dependent membrane association dynamics and microdomain partitioning of Ras proteins. Methods. 40:183-190. 2006
- Nonconventional trafficking of Ras associated with Ras signal organization. Traffic. 7:1119-1126. 2006
- Spatiotemporal organization of Ras signaling: rasosomes and the galectin switch. Cellular and Molecular Neurobiology. 26:469-493. 2006
- Ras and its signals diffuse through the cell on randomly moving nanoparticles. Cancer research. 66:1974-1981. 2006
- Individual palmitoyl residues serve distinct roles in H-ras trafficking, microlocalization, and signaling. Molecular and cellular biology. 25:6722-6733. 2005
- Three separable domains regulate GTP-dependent association of H-ras with the plasma membrane. Molecular and cellular biology. 24:6799-6810. 2004
- Galectin-1 (L11A) predicted from a computed galectin-1 farnesyl-binding pocket selectively inhibits Ras-GTP. Cancer research. 64:3112-3118. 2004