Tissue factor activity in women with preeclampsia or SGA: a potential explanation for the excessive thrombin generation in these syndromes Academic Article uri icon


  • Abstract Objective: The aim of this study was to determine whether the activity of tissue factor (TF) and tissue factor pathway inhibitor (TFPI) in the plasma of women with preeclampsia (PE) and small for gestational age (SGA) neonate differ from that of normal pregnant women and whether they are related to specific placental lesions. Methods: This cross-sectional study included the following groups:(1) normal pregnancy (n= 68);(2) PE (n= 128); and (3) SGA (n= 56). Maternal plasma TF and TFPI activity was determined with chromogenic …

publication date

  • May 18, 2017