The impact of PCR on Clostridium difficile detection and clinical outcomes Academic Article uri icon


  • PCR has increasingly replaced toxin A and B enzyme immunoassay (EIA) for the testing of Clostridium difficile infection (CDI). This study evaluated the clinical outcomes of CDI and disease epidemiology since the introduction of PCR. Clinical data and outcomes for patients admitted to a tertiary care centre during 2003 to 2012 were extracted using electronic medical records. Outcomes and incidence of disease were compared between types of CDI testing. In total, 15.6% of 108 092 patients admitted were tested for CDI. Among patients …

publication date

  • September 1, 2015