Multicentric Castleman's disease associated with rheumatoid arthritis: A possible role of hepatitis B antigen Academic Article uri icon


  • A patient with seropositive rheumatoid arthritis and a carrier of hepatitis B surface antigen developed angiofollicular hyperplasia (multicentric Castleman's disease). The hepatitis B virus and the rheumatoid factor may have had a role in the aetiology of this lymphatic disorder. The development of Castleman's disease in association with these factors may provide another clue supporting the reactive nature of this disease.

publication date

  • May 1, 1989