Correlation of Functional and Binding Antibody Responses Elicited by 13-valent and 7-valent Pneumococcal Conjugate Vaccine and Association With Nasopharyng... Academic Article uri icon

abstract

  • ABSTRACT In a randomized, double-blind trial in healthy Israeli infants in Israel who received 13-valent or 7-valent pneumococcal conjugate vaccine (PCV13 or PCV7) at 2, 4, 6, and 12 months, PCV13 significantly reduced nasopharyngeal (NP-) colonization of serotypes 1, 6A, 7F, 19A, cross-reacting 6C, and the common PCV7 serotype 19F, from age 7 to 24 months. No differences were observed between vaccine groups for serotype 3 or for the remaining common PCV7 serotypes. For serotype 5, too few events were observed to …

publication date

  • July 2, 2014