Safety and Efficacy of Excitatory Repetitive Deep Transcranial Magnetic Stimulation with H-Coil: An Open Study in 24 Patients with Parkinson's Disease (P04. 185) Academic Article uri icon


  • OBJECTIVE: To evaluate the safety and efficacy of repetitive Deep Transcranial Magnetic Stimulation (DTMS) in Parkinson's Disease (PD), using the novel H-coil. BACKGROUND: Repetitive transcranial magnetic stimulation has proved to be able to modify cortical excitability and to be effective in Parkinson's disease, especially when applied with high frequencies. DESIGN/METHODS: 24 PD-patients (aged 60±6.7; PD-duration: 6.6±3; motor Unified Parkinson's Disease Rating Scale-UPDRSIII: 38.8±10.5) underwent 12 DTMS sessions in 4 weeks, over primary motor (M1) of the most affected hemisphere and bilateral prefrontal (PF) regions at excitatory 10Hz frequency. Clinical assessment included total UPDRSIII and partial scores, for the worse (WS) or less affected (LS) PD-side, for axial involvement (AS), tremor (TS) and rigidity (RS). Four timed tests (arm tapping-AT; Nine …

publication date

  • January 1, 2013