Microfluidic biofilm observation, analysis, and treatment (Micro-BOAT) platform Academic Article uri icon


  • ABSTRACT We present the first demonstration of a novel bacterial biofilm treatment technique showing a 56% average decrease in bacterial cell viability compared to traditional antibiotic treatments in a Micro-BOAT platform. Integrated linear array charge-coupled devices achieve spatially realized optical density monitoring, correlating to both average biomass and localized biofilm morphology. For on-chip demonstration of biofilm treatment, a unique bioelectric effect using a superpositioned direct and alternating current electric …

publication date

  • January 1, 2012