Reversal of Motor Symptoms in Parkinson’s Disease using Deep TMS with the H1 Coil: Longitudinal Case Series Academic Article uri icon


  • Background Repetitive transcranial magnetic stimulation has been proposed as a non- surgical method of treatment for medicated Parkinson's disease patients with residual motor symptoms. Objective We report here the treatment of two patients with Parkinson's disease using the H1 deep TMS coil that is currently FDA cleared for depression. Methods We selected a TMS protocol combination that would suppress over the motor cortex and subsequently stimulate over the prefrontal cortex. We utilized the H1 coil over the motor cortex 1HZ, 110% MT, 1000 total pulses, followed by an additional 2000 pulses over the prefrontal cortex in a high intensity, high frequency protocol. Results Both patients demonstrated substantial improvement in total Unified Parkinson's Disease Rating Scale (UPDRS) scores. The male patient's UPDRS dropped from 90 to 37 and the female's …

publication date

  • September 1, 2014