617: Maternal hypothyroidism and risk of endocrine morbidity in the offspring Academic Article uri icon


  • Objective Previous studies suggested maternal hypothyroidism during pregnancy to be associated with cognitive impairment of the offspring. Scares data exist regarding long term endocrine health of the offspring. This study aimed to assess whether children born to mothers with hypothyroidism during pregnancy are at an increased risk for long-term endocrine morbidity. Study Design A retrospective population-based cohort study, in a tertiary regional medical center, compared long-term endocrine morbidity of children born to mothers with and without hypothyroidism. Deliveries occurred between the years 1991- 2014. Multiple gestations, fetuses with congenital malformations, and women lacking prenatal care were excluded. Hospitalizations of the offspring up to the age of 18 years involving endocrine morbidity were evaluated according to a pre-defined set of ICD-9 …

publication date

  • January 1, 2018