The impact of the ovarian stimulation protocol and the luteal support on IVF outcome in women with recurrent implantation failure Academic Article uri icon


  • Objective To investigate the relationship between the pregnancy rates and the medications used during and after an IVF cycle among patients with recurrent implantation failure (RIF). Design A retrospective cohort study of 854 IVF cycles in 183 patients was conducted. It has included patients of less than 35 years old with at least three failed fresh IVF cycles. Materials and Methods We have analyzed the relation between the probability of pregnancy and the following criteria: IVF protocol, types of gonadotropins, type of luteal support and IVF outcome. Results Pregnancy rates were similar regardless of the protocol employed. Nevertheless, while comparing a small sub-group of 8 patients who conceived using follitropin beta (Puregon) for ovarian stimulation with 25 patients treated with follitropin alpha (Gonal F), a significantly increased pregnancy rate was noted in the follitropin beta group …

publication date

  • January 1, 2014