Epidemiological information is key when interpreting whole genome sequence data–lessons learned from a large Legionella pneumophila outbreak in Warstein, Ge... Academic Article uri icon

abstract

  • Legionella spp. is the causative agent of Legionnaires' disease (LD) named after its first occurrence during a convention of the American Legion in 1976 [1, 2]. These rod shaped Gram-negative bacteria inhabit all kinds of natural and man-made fresh water reservoirs including cooling towers (CT), spas and drinking water systems. Inhalation of legionellae- containing aerosols originating from contaminated environmental reservoirs is the main route of infection. However, a case of a personto-person transmission of Legionella under special circumstances was recently reported [3]. LD accounts for 2–20% of community- acquired pneumonia (CAP) and the number of cases in Europe reached almost 6,000 in 2014 [4]. In Germany ca 1,000 cases are reported annually, representing an incidence of ca 11 cases per million population [5]. In Europe ca 10% of the cases are related to clusters …

publication date

  • November 9, 2017