Decidual NK cells regulate key developmental processes at the human fetal-maternal interface Academic Article uri icon


  • RESULTS dNK cells produce chemokines and angiogenic factors To gain insight into the unique function of dNK cells in the decidua, we performed microarray analysis on purified dNK cells (Fig. 1a, b and Supplementary Tables 1 and 2 online). We aimed to obtain a transcriptional profile of secreted cytokines, chemokines and growth factors in dNK cells that are thought to be involved in two developmental processes that are crucial for placental development: trophoblast invasion and vascular growth1. Transcripts encoding several …

publication date

  • January 1, 2006