P. 1. j. 003 Diffusion tensor imaging in posttraumatic patients: the role of the corpus-callosum in PTSD symptomatology and memory impairments Academic Article uri icon


  • Several neuroimaging studies in PTSD have revealed structural differences in specific gray- matter regions (eg anterior cingulate cortex, hippocampus and the amygdala) with smaller cortical volumes frequently reported in traumatic patients. Recently, whitematter alterations have become a target for extensive research in post-traumatic stress disorder (PTSD), with a recent review concluding that overall, reductions in white-matter volume were more often reported than increases [1]. While these studies show promise for further characterization of PTSD-related abnormalities, most critical in these studies is the absence of evidence for clinical correlates between PTSD symptomatology and cognitive measures and the reported imaging results. The aim of the current study was to examine to what extent white-matter integrity is associated with symptomatology and memory in PTSD. 16 PTSD patients and …

publication date

  • January 1, 2014