- In this paper we propose a new approach of signal conditioning circuits. The circuit is able to handle both electrochemical and bioluminescent sensors, mainly electrochemical sensors. The integrated circuit will convert electrical signal into impulses, making the frequency the carrier of the information. In this way we avoid amplifying stages, reducing circuit complexity and area on chip. The biggest obstacles that we manage to overcome ware the major difference between the currents provided by the sensors and the sense of the currents. We still need to build an interface capable to work not only with one sensor but with 6X6 or 8X8 sensors.