Comparison of superficial TMS and deep TMS for major depression Academic Article uri icon


  • Background Traditionally TMS treatment sessions for MDD were administered over the DLPFC using a focal superficial figure-8 coil. Recently the FDA has cleared deep TMS treatment for MDD using Brainsway H-coil, following a large DBPC multi-center study. The induced electric field characteristics, stimulated brain structures and clinical outcomes are very disparate between the two methods. Methods Electric field characteristics of figure-8 coil and of the H1-coil were measured in a realistic head model filled with physiologic saline concentration, and maps of field distribution were produced. We review several studies discussing brain structures and networks which are relevant for clinical outcome in MDD, and discuss the implications of the spatial characteristics of each TMS coil. Results Where using 120% of MT the H1-coil induces supra-threshold fields at depth of 1.8 cm and …

publication date

  • September 1, 2014