The association between adherence to cardiovascular medications and healthcare utilization Academic Article uri icon


  • Background Poor adherence to medications for cardiovascular disease (CVD) is associated with adverse health outcomes, but little is known about its association with healthcare utilization (HCU). Objective To examine whether adherence is associated with a long-term decrease in HCU. Methods This is a retrospective cohort study of 1582 patients with CVD who enrolled in Maccabi Healthcare Services in Israel, initiating CVD medication therapy in 2006. Adherence was assessed by the proportion of days covered (PDC) with medications. Patients were defined as: non-adherent (PDC< 0.4), partially adherent (0.4≤ PDC< 0.8), and fully adherent (PDC≥ 0.8). HCU was estimated for 4 years following treatment initiation. Multivariable GEE models were used to analyze predictors of HCU. Model I included total adherence during the entire follow-up period as well as the interaction between this …

publication date

  • January 1, 2016