592: Long term endocrine disorders in children following assisted reproductive technology (ART) pregnancies compared with spontaneous pregnancies Academic Article uri icon


  • Objective To determine the risk of long-term endocrine disorders among children born after in-vitro fertilization (IVF) and ovulation induction (OI) as compared with spontaneous pregnancies. Study Design A population-based cohort study including all singleton deliveries occurring between the years 1991-2013 at a single tertiary medical center was performed. Fetuses with congenital malformations were excluded. Children delivered following pregnancies achieved by IVF, OI, and spontaneous pregnancies were compared. Hospitalization rates up to the age of 18 years involving endocrine disorders were evaluated. Endocrine disorders evaluated included thyroid disorders, insulin and non- insulin dependent diabetes mellitus, hypoglycemia, hyperlipidemia, obesity, para-thyroid disorders, and adrenal and sex hormone disorders. A Kaplan-Meier survival curve was …

publication date

  • January 1, 2017