439 Use of Amplitude Integrated Electroencephalography (AEEG) in Patients with Inborn Errors of Metabolism - a Review of 29 Cases Academic Article uri icon


  • Background: Amplitude integrated EEG (aEEG) has been established in neonatal care as tool to monitor encephalopathy after asphyxia and seizures due to various aetiologies. Patterns representing seizures and different degrees of encephalopathy have been defined. Patients with inborn errors of metabolism often present with encephalopathy/seizures but published knowledge regarding aEEG use in metabolic patients remains limited as disease frequencies are low. Aims: Review aEEG tracings of patients with inborn errors of metabolism to evaluate the potential role of this technique in evaluation/treatment of this patient group. Methods: Through an international collaboration, 29 aEEG tracings of patients with inborn errors of metabolism were collected and reviewed. Results: Diagnoses were: disorders of energy metabolism (n= 10), disorders of amino or organic acid metabolism …

publication date

  • November 1, 2010