- Nonlinear non-Gaussian state-space models arise in numerous applications in control and signal processing. In this context, one of the most successful and popular approximation techniques is sequential Monte Carlo (SMC) methods, also known as particle filters. Nevertheless, these methods tend to be inefficient when applied to high dimensional problems. In this paper, we present an overview of Markov chain Monte Carlo (MCMC) methods for sequential simulation from posterior distributions, which represent efficient alternatives to SMC methods. Then, we describe an implementation of this MCMC-Based particle algorithm to perform the sequential inference for multitarget tracking. Numerical simulations illustrate the ability of this algorithm to detect and track multiple targets in a highly cluttered environment.