Bifunctional Carbon-Dot-WS2 Nanorods for Photothermal Therapy and Cell Imaging Academic Article uri icon

abstract

  • Multifunctional nanoparticles have attracted significant interest as biomedical vehicles, combining diagnostic, imaging, and therapeutic properties. We describe herein the construction of new nanoparticle conjugates comprising WS 2 nanorods (NRs) coupled to fluorescent carbon dots (C-dots). We show that the WS 2-C-dot hybrids integrate the unique physical properties of the two species, specifically the photothermal activity of the WS 2 NRs upon irradiation with near-infrared (NIR) light and the excitation-dependent luminescence emission of the C-dots. The WS 2-C-dot NRs have been shown to be non-cytotoxic and have been successfully employed for multicolour cell imaging and targeted cell killing under NIR irradiation, pointing to their potential utilization as effective therapeutic vehicles.

publication date

  • January 1, 2017