Photoinacttvation of a Portion of a Neurone for Long-Term Studies of its Role in Behaviour Academic Article uri icon

abstract

  • An important method in the study of the neural basis of behaviour is the removal from a nerve circuit of a single cell in vivo and the subsequent search for changes in behaviour (Atkins et al. 1984; Comer, 1985). In such studies it can also be useful to remove only a part of a cell, such as a segment of its dendritic tree or axon. This can be done by filling the cell with the fluorescent dye Lucifer Yellow (LY) and irradiating the particular segment to be removed (Jacobs & Miller, 1985). However, for behavioural testing, it is often necessary to …

publication date

  • March 1, 1989