In: Industrial Application of Biotechnology ISBN 1-60021-039-2 Editors: IA Krylov and GE Zaikov, pp. 9-16© 2006 Nova Science Publishers, Inc. Academic Article uri icon


  • Very long-chain polyunsaturated fatty acids (VLC-PUFAs) of the ro3 family are quite abundant in microalgae, however, co6 VLC-PUFA are relatively rare [Cohen et al, 1992]. Arachidonic acid (AA, 20: 4co6) is almost excluded from the lipids of fresh water algae and in most marine species it does not accumulate in the biomass [Bigogno et al, 2002]. When present, VLC-PUFAs are predominantly located in the polar lipids of membranes, whereas triacylglycerols (TAG) generally contain very little VLC-PUFAs [Cohen, 1999]. The ability of cells to accumulate VLC-PUFAs is intrinsically limited in most algae, since these fatty acids are generally components of membrane lipids which content is strictly regulated. Nevertheless, certain algal species can be induced to synthesize and accumulate extremely high proportions of TAG [Shifrin and Chisholm, 1981]. An algal strain has been isolated …

publication date

  • January 1, 2006