Session 58: Fertility Preservation 2 Academic Article uri icon


  • Materials and Methods: Data were pooled from two Phase II, randomized, placebo- controlled, double-blind studies performed at the National Institutes of Health (USA). Women aged 25–50 years with symptomatic uterine fibroids were randomized to receive UPA (10 or 20 mg) or placebo once daily for three menstrual cycles (or 90–102 days, if amenorrheic). Outcomes included magnetic resonance imaging-determined total fibroid volume change at the end of treatment (percentage change from baseline), amenorrhea, change in serum …

publication date

  • January 1, 2010