Correlation of slow spontaneous neuronal fluctuations across hemispheres in human sensory cortex Academic Article uri icon

abstract

  • Recent functional magnetic resonance imaging (fMRI) studies reveal the presence of spontaneous fluctuations of activity in human sensory cortex emerging in the complete absence of external stimuli or task. Such fluctuations show remarkable selectivity for functional networks, coherence across large cortical distances and across hemispheres, yet it is currently unknown what neuronal dynamics may underlie this spontaneous activity in the human brain. We studied this question by combining bilateral single-unit, local field potentials (LFPs), and intra-cranial electrocorticography (ECoG) recordings in patients undergoing clinical monitoring. We found very slow (< 0.1 Hz, following 1/f profiles) spontaneous waves of neuronal activity exhibiting significant interhemispheric correlations. These correlated waves were evident mainly in neuronal firing rates and in gamma (40 …

publication date

  • January 1, 2008