- Diffuse or multifocal seeding of the leptomeninges by carcinoma, so-called meningeal carcinomatosis, often presents as simultaneous or rapidly sequential cranial neuropathy, with or without headache, altered mental status, or signs of meningeal irritation. Visual loss may occur in up to 30% of these patients, usually rapid, painless, and unilateral, and often progressing to the other eye. 1 Only a few cases of meningeal carcinomatosis owing to ovarian carcinoma have been reported. To the best of our knowledge there are no reports in the literature on acute bilateral blindness occurring during hours owing to meningeal carcinomatosis or ovarian malignancies. We present a case of acute bilateral blindness secondary to ovarian adenocarcinoma with meningeal infiltration.