497: Angiogenic factors vs. standard evaluation in the prediction of adverse outcome among pregnancies with suspected fetal growth restriction Academic Article uri icon


  • Objective Prediction of adverse neonatal outcome in growth restricted fetuses (FGR) is challenging. Currently, standard evaluation includes Doppler surveillance and repeated clinical assessments. While this management protocol identifies most anticipated complications, some cases are missed and the health-care provider's ability to predict adverse outcome may be improved. We studied the added value of angiogenic factors in management of FGR cases for the prediction of adverse perinatal outcomes. Study Design This prospective cohort study included hospitalized women with singleton pregnancies diagnosed with FGR between 24 and 35+ 6 weeks' gestation (n= 58). At hospitalization blood was drawn from women for sFlt-1 and PlGF measurements. Hence, three attending maternal-fetal medicine (MFM) assessed the risk of these pregnancies to develop …

publication date

  • January 1, 2018