Low Frequency Repetitive Deep Transcranial Magnetic Stimulation Improves Motor Performance in Patients with Parkinson's Disease (P02. 235) Academic Article uri icon

abstract

  • Objective: To test the safety and efficacy of the H-coil as a treatment for PD. Background Repetitive transcranial magnetic stimulation (rTMS) using the new H-coil, allowing stimulation of deeper neuronal pathways, can cause short term, modest improvement of some motor measures in PD Design/Methods: 20 PD patients with asymmetric involvement were randomized to one of two treatment protocols: 1. Low frequency (1Hz) stimulation over the motor cortex along with high frequency stimulation (10Hz) over the prefrontal cortex. 2. Low frequency stimulation over the motor cortex alone. Patients had 12 treatment sessions in 30 days period. Outcome measures, collected on days 1, 10, 30 and 60 included: Unified PD rating scale (UPDRS), Clinical Global Impression of severity and change scales (CGIS and CGIC), pegboard test, foot and finger tapping tests, timed Up & Go test (TUG), as well …

publication date

  • January 1, 2012