610: Maternal hypothyroidism and future pediatric neurological morbidity of the offspring Academic Article uri icon


  • Objective Maternal hypothyroidism in pregnancy has been associated with cognitive impairment in exposed children. We sought to evaluate the long-term pediatric neurological morbidity of children to mothers with known hypothyroidism during pregnancy. Study Design A population-based cohort analysis was performed including all deliveries occurring between 1991-2014 at a regional tertiary medical center. Multiple gestations, fetuses with congenital malformations, and women lacking prenatal care were excluded. Hospitalizations of the offspring up to the age of 18 years involving neurological morbidity were evaluated according to a predefined set of ICD-9 codes, including autistic and developmental disorders, eating, sleeping and movement disorders, cerebral palsy and more. A Kaplan- Meier survival curve was used to compare cumulative hospitalization rate in exposed and …

publication date

  • January 1, 2018