Transcranial Magnetic Stimulation Improves Retinal Function in an Animal Model of Retinal Dystrophy Academic Article uri icon

abstract

  • Purpose:: To evaluate the effect of transcranial magnetic stimulation (TMS) on retinal function in Royal College of Surgeons (RCS) rats. Methods:: Four weeks old RCS rats underwent electroretinogram (ERG) before TMS treatment and followed weekly for 7 weeks (11 weeks follow-up). A total of 24 rats received 6 or 12 sessions (1-2 or 1-4 weeks, respectively) of either real (active, n= 8/group) or sham (placebo, n= 8/group) TMS over the right eye. Evaluation of effects was performed using ERG in scotopic and photopic conditions every week in each eye. Results:: Two weeks of treatment (6 sessions) indicated a delayed and transient improvement in the scotopic maximal negative ERG responses in each eye (24% and 102% of change improvement compared to placebo in the right and left eye respectively, 4 and 5 weeks after treatment p< 0.05). Extending the treatment to four …

publication date

  • March 26, 2012