The impact of depression on the treatment of obsessive-compulsive disorder: results from a 5-year follow-up Academic Article uri icon


  • Background Many OCD patients present with comorbid conditions, and major depression is one of the most frequent comorbidities observed. OCD patients with comorbid depression exhibit functional disability and poor quality of life. However, it is unclear whether depressive symptoms are predictive of treatment response, and debate remains whether they should be targeted in the treatment of comorbid patients. The current study aimed at assessing the predictive value of depression and OCD symptoms in the long term outcome of OCD treatment. Methods In the current study, relations between OCD and depressive symptoms were systematically investigated in a group of 121 OCD patients who received 16 sessions of behavior or cognitive therapy either alone or with fluvoxamine. Results Depression (either as a continuous or categorical variable) was not predictive of treatment response in any of …

publication date

  • December 1, 2011