Isolated congenital histiocytosis in the palpebral conjunctiva in a newborn Academic Article uri icon

abstract

  • Purpose To report a rare case of congenital histiocytosis in a newborn without skin involvement. Design Interventional case-report. Methods A full-term baby presented with a mass over the palpebral conjunctiva of his left upper lid. Ophthalmic examination was otherwise normal, and the baby was healthy. There were no skin lesions. Results The lesion was completely removed surgically. Pathologic examination demonstrated a cellular infiltrate composed of eosinophils and histiocytes. Immunohistochemistry disclosed positive stain for protein S-100 and CD1 antigenic determinant. Pediatric oncology evaluation was completely normal. Eighteen months after presentation, the patient remained healthy without recurrence of the lesion. Conclusions Rare cases of congenital histiocytosis can present as a solitary lesion over the palpebral conjunctiva, without skin or systemic involvement.

publication date

  • January 1, 2005