Interleukin-1 inhibits sexual behavior in female but not in male rats Academic Article uri icon


  • The cytokine interleukin-1 (IL-1) is released by a variety of cells in response to infection or injury. IL-1 produces several neuroendocrine and behavioral effects, including a suppression of reproductive functions and goal-directed behaviors. The present study examined the effect of IL-1 on sexual behavior in male and female rats. The following behavioral tests were employed: preference for a sexually appropriate partner, preceptive (soliciting) behavior, the lordosis quotient (sexual receptivity), and mating performance …

publication date

  • September 1, 1995