PP060-SUN HEPATIC FAT IS DIFFERENTIALLY-ASSOCIATED WITH SUPERFICIAL VERSUS DEEP ABDOMINAL SUBCUTANEOUS ADIPOSE TISSUES SUB-DE... Academic Article uri icon

abstract

  • Results: Across the participants (age= 47.6 years, 31 women) men [HFP= 10.8%, Waist circumference (WC)= 107.7 cm, visceral adipose tissue (VAT)= 28.9%, deep subcutaneous adipose tissue (DSAT)= 45.4%, superficial SAT (SSAT)= 23.6%] had higher HFP than women [HFP= 6.4%, WC= 99.4 cm, VAT= 20.1%, DSAT= 38%, SSAT= 38.1%; p= 0.001). In multivariate regression model% VAT (beta= 0.315; p< 0.001) and% DSAT (beta= 0.13; p= 0.044) were independently and directly associated with hepatic fat but not with% SSAT (beta= 0.036; p= 0.569). Further independent predictors were TG (beta= 0.204; p< 0.001), HDL-c (beta= 0.129; p= 0.023) and serum ALT levels (beta= 0.307; p< 0.001). Conclusion: While visceral and DSAT abdominal fat are independently related to increased HFP, SSAT remains neutral, suggesting differential roles of abdominal fat sub-depots with liver …

publication date

  • September 1, 2013