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  • This survey determined the proportions of S. pneumoniae and H. influenzae isolates with resistance to antibacterial agents such as penicillin, tetracycline, erythromycin and clindamycin among patients aged less than 18 years and adults. Among S. pneumoniae isolates, penicillin resistance increased from 1989 to a peak of 25% in 1999, with a decline to 18% in 2007; resistance to macrolides and tetracycline increased during the surveillance period. The article also examines the possible impact of multivalent pneumococcal vaccines on the antimicrobial resistance profiles of pneumococcal isolates in young children (< 6 years old), based on vaccine-mediated changes in serotype prevalence. The authors highlight the need for continued epidemiological monitoring of serotype prevalence and antimicrobial resistance, with the introduction of new, extended-cover conjugate …

publication date

  • January 1, 2010