Respiratory Mechanics and Lung Stress in Acute Lung Injury - Impact of End-Expiratory Pleural and Airway Pressures. Conference Paper uri icon

abstract

  • B106 MECHANISMS OF VENTILATOR ASSOCIATED LUNG INJURY / Poster Discussion / Monday, May 18/1:30 PM−4:00 PM … Room 16 A−B (Mezzanine Level) San Diego Convention Center … Respiratory Mechanics and Lung Stress in Acute Lung Injury — Impact of End−Expiratory Pleural and Airway Pressures … D. Talmor, MD 1,2 , T. Sarge, MD 1,2 , A. Malhotra, MD 1,2 , C. O'Donnell, ScD 1,2 , R. Ritz, RRT 1,2 , V. Novack, MD 1,2 and SH Loring … MD 1,2 . Email: dtalmor@bidmc.harvard.edu … 1 Beth Israel Deaconess Medical Center, Boston, MA and … Introduction Recent studies have focused on airway pressure and transpulmonary pressure (Ptp) as the key determinates of lung stress and strain. These analyses do not account for the influence of the initial pressures that represent the “pre−stress” state of the lung and could have a major impact on the “post−stress” state after inflation. We hypothesize that the …

publication date

  • April 1, 2009