The pre-weaning maternal environment does not modulate the BP response to salt in the Sabra rat model of hypertension Academic Article uri icon

abstract

  • Background: Previous studies in SHR and Dahl rats have shown a significant impact of the maternal environment on the evolution of the BP phenotype. SHR raised by Wistar-Kyoto or Sprague-Dawley had attenuation of BP at 3 months. Similarly, Dahl S rats nurtured prior to weaning by Dahl R had a lower BP. In addition, in SHR and Dahl S, maternal environment has been demonstrated to have a significant impact on the BP response to salt.

publication date

  • June 1, 2000