824: Maternal asthma during pregnancy and the risk for future long-term infectious morbidity in the offspring Academic Article uri icon

abstract

  • Objective Asthma is a common disease featuring immune system dysfunction. While substantial evidence supports the notion that the atopic tendencies pass throughout generations, the link to other immune disorders is limited. We therefore aimed to assess whether maternal asthma increases the risk for long-term infectious morbidity in the offspring. Study Design In this retrospective population-based cohort study, we compared long-term infectious morbidity in offspring following pregnancies exposed and unexposed to maternal asthma. Deliveries occurred in a single regional tertiary medical center between the years 1991-2014. Congenital malformations and multiple pregnancies were excluded from the study. A survival curve and a Cox regression model were used to assess the association and control for confounders. Results During the study period 242,187 …

publication date

  • January 1, 2018