Epidemiology of invasive childhood pneumococcal infections in Israel Academic Article uri icon


  • Objective. —To study the epidemiology of childhood pneumococcal invasive infections in Israel as a background for immunization programs. Design. —A 2-year (October 1988 through September 1990) prospective, nationwide surveillance of all invasive pediatric pneumococcal infections. Setting. —All 25 medical centers hospitalizing children in Israel, including all laboratories performing blood cultures from pediatric patients. Patients. —Infants and children aged 0 to 12 years visiting the pediatric emergency department or hospitalized in pediatric departments were included if Streptococcus pneumoniae was isolated from blood or cerebrospinal fluid. Results. —Four hundred sixty-nine invasive infections were diagnosed. Pneumonia, bacteremia without apparent focus, meningitis, and cellulitis were found in 39%, 37%, 17%, and 3%, respectively. The annual incidence was 42 per 100000 for children younger than 5 years of age (104 per 100000 for those Conclusions. —Pneumococcal invasive infections are common in children in Israel and carry considerable morbidity. ( JAMA . 1992;268:3328-3332)

publication date

  • January 1, 1992

published in