Perimenstrual psychosis among female adolescents: two case reports and an update of the literature Academic Article uri icon


  • Objectives and Methods: Perimenstrual psychosis is an uncommon disorder not included under the accepted classifications of functional psychoses. Our aim was to describe two Israeli female adolescents who fit this diagnosis. Results: Both youngsters developed an acute psychosis a few days before menstruation which subsided several days after bleeding only to reappear in the same form in subsequent cycles. An extensive medical work-up did not show any significant disturbances with the exception of anovulatory cycles in one youngster. Psychotropic treatment had no effect on the course of the psychosis. Treatment with a combined progesterone/estrogen contraceptive agent in one patient resulted in full recovery within several cycles. The second patient showed a spontaneous remission within four cycles. Follow-up for two to three years indicated a complete remission with no need to reintroduce any psychotropic agent. Conclusions: Perimenstrual psychosis may represent a cycloid disorder or an atypical affective disorder associated with anovulation. The use of psychotropic treatment is considered inconclusive whereas hormonal agents may prove effective. (authors)

publication date

  • January 1, 2003