730: Prenatal maternal smoking and offspring respiratory morbidity: Results of a population based cohort study Academic Article uri icon


  • Objective Maternal prenatal smoking is known to adversely affect pregnancy course and outcome. We aimed to evaluate the association between maternal prenatal smoking and the long-term risk for pediatric respiratory morbidity in the offspring, up to the age of 18 years. Study Design A population based cohort analysis was performed comparing the risk for long- term pediatric respiratory related hospitalizations, among children born to mothers who smoked during pregnancy versus those who did not. Pediatric respiratory related morbidities were pre-defined based on ICD-9 codes, as recorded in the hospital computerized medical files. Deliveries occurred between the years 1991-2014 at a regional tertiary medical center. Kaplan-Meier survival curves were used to compare cumulative respiratory related hospitalizations in both groups over time and Cox proportional hazards models were …

publication date

  • January 1, 2018