PLACENTAL TRANSFER OF POLIOVIRUS ANTIBODIES IN FULL-TERM AND PRETERM BIRTHS.??? 1768 Academic Article uri icon

abstract

  • Objective: To investigate the transplacental transfer of maternal poliovirus antibodies in full- term and preterm births. Subjects: Two hundred healthy, Israeli born mothers participated in the study. They were divided into 2 grps: a full-term grp with 150 consecutive births above 37 weeks of gestation and the preterm grp with gestational age less than 35 weeks. Maternal and umbilical cord blood samples were taken in all cases. Serology: Antibody titers against the three poliovirus serotypes and the epidemic type 1 strain were measured by microneutralization system. Results: The percentages of protective poliovirus titers (1: 8 or above) and their geometrical means (GMT) in mothers and cord bloods in the full-term and preterm groups, are presented in the table. The GMT's against poliovirus types 1, 1 epidemic and 3 were significantly lower in the preterm compared to full-terms. A significant linear …

publication date

  • January 1, 1996