- MIL-STD-1553 is a military standard that defines the physical and logical layers, and a command/response time division multiplexing of a communication bus used in military and aerospace avionic platforms for more than 40 years. As a legacy platform, MIL-STD-1553 was designed for high level of fault tolerance while less attention was taken with regard to security. Recent studies already addressed the impact of successful cyber attacks on aerospace vehicles that are implementing MIL-STD-1553. In this study we present a security analysis of MIL-STD-1553. In addition, we present a method for anomaly detection in MIL-STD-1553 communication bus and its performance in the presence of several attack scenarios implemented in a testbed, as well as results on real system data. Moreover, we propose a general approach towards an intrusion detection system (IDS) for a MIL-STD-1553 communication bus.