653: Maternal uterine leiomyoma and long-term pediatric morbidity in the offspring Academic Article uri icon


  • Objective Short term perinatal implications in pregnancies with uterine leiomyoma include lower ongoing pregnancy rates, higher rates of fetal malpresentation and preterm delivery. The potential long-term impact on offspring however, has not been investigated. The present study aimed to investigate the long-term morbidity in offspring of mothers with uterine leiomyomas. Study Design A population-based cohort analysis including all singleton deliveries which occurred between the years 1991-2014 at a single regional tertiary medical center was conducted. Long-term hospitalizations of the offspring, up to the age of 18 years, due to gastrointestinal, neurological, cardiovascular, endocrine, and respiratory morbidity were assessed, following pregnancies diagnosed with and without uterine leiomyoma. Fetuses with congenital malformations and multiple pregnancies were excluded. Kaplan …

publication date

  • January 1, 2018