The pattern and magnitude of “in vivo thrombin generation” differ in women with preeclampsia and in those with SGA fetuses without preeclampsia Academic Article uri icon


  • Abstract Objective: We aimed to determine the differences in the pattern and magnitude of thrombin generation between patients with preeclampsia (PE) and those with a small-for- gestational-age (SGA) fetus. Methods: This cross-sectional study included women in the following groups:(1) normal pregnancy (NP)(n= 49);(2) PE (n= 56); and (3) SGA (n= 28). Maternal plasma thrombin generation (TGA) was measured, calculating:(a) lag time (LT);(b) velocity index (VI);(c) peak thrombin concentration (PTC);(d) time-to-peak thrombin …

publication date

  • January 1, 2018