The biosynthetic pathway of astaxanthin in a green alga Haematococcus pluvialis as indicated by inhibition with diphenylamine Academic Article uri icon


  • Abstract The effect of diphenylamine on astaxanthin biosynthesis in Haematococcus pluvialis was studied. Cultures induced to produce astaxanthin accumulated rβ-carotene in the presence of the inhibitor. It was found that 30 μM diphenylamine specifically inhibits the biosynthesis of astaxanthin at the step of conversion of rβ-carotene to echinenone and canthaxanthin. The results imply that these two compounds are genuine intermediates in the pathway of astaxanthin biosynthesis in H. pluvialis.

publication date

  • January 1, 1995