Interdisciplinary Physics: Biological Physics, Quantum Information, etc.-Long Term Behavior of Lithographically Prepared In Vitro Neuronal Networks Academic Article uri icon


  • Abstract We measured the long term spontaneous electrical activity of neuronal networks with different sizes, grown on lithographically prepared substrates and recorded with multi- electrode-array technology. The time sequences of synchronized bursting events were used to characterize network dynamics. All networks exhibit scale-invariant Lévy distributions and long-range correlations. These observations suggest that different-size networks self- organize to adjust their activities over many time scales. As predictions of current models …

publication date

  • January 1, 2002