Reaction of 1-bromo-2-acylacetylenes with thiobenzhydrazide Academic Article uri icon

abstract

  • The reactions of 1-bromo-2-acylacetylenes with thiobenzhydrazide at from -10 to -30°C in ether, acetonitrile, methanol without catalyst, or methanol in the presence of triethylamine gave 2-acylmethyl-5-phenyl-1,3,4-thiadiazoles and their hydrobromide salts.

publication date

  • January 1, 1988