Chronic urticaria and the metabolic syndrome: a cross-sectional community-based study of 11 261 patients Academic Article uri icon


  • Background Emerging evidence suggests that chronic urticaria (CU) is associated with chronic, low-grade, inflammatory process. Objective To evaluate the association between CU and metabolic syndrome and its components in a large community-based medical database. Methods A cross-sectional study of CU patients and matched controls was performed. CU was defined as eight urticaria diagnoses (with each two diagnoses registered within a period of 6 weeks) from 2002 to 2012. Data regarding the prevalence of metabolic syndrome, its components and possible complications were collected. Results The study included 11 261 patients with CU and 67 216 controls. In a univariate analysis, CU was significantly associated with higher body mass index (BMI) and a higher prevalence of obesity, diabetes, hyperlipidaemia, hypertension, metabolic syndrome, chronic renal …

publication date

  • February 1, 2018